Identification of link proteins in canine synovial cell cultures and canine articular cartilage

Identification Cultures and of Link Proteins in Canine Synovial Cell Canine Articular Cartilage

Link proteins are glycoproteins in cartilage that are involved in the stabilization of aggregates of proteoglycans and hyaluronic acid. We have identified link proteins in synovial cell cultures from normal canine synovium using sodium dodecyl sulfate-polyacrylamide gel electrophoresis, immunofluorescence, and immunolocation with specific antibodies by electrophoretic transfer. We have also fou...

Articular Cartilage Regeneration Using Intra-articular Injection of Allogeneic Synovium-derived Mesenchymal Stem Cells in A Canine Model

Bone Alkaline Phosphatase in Synovial Fluid Is Correlated to Radiographic Osteophyticchanges in a Canine Cranial Cruciate Transection Model of Osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is considered to be a complex disease process that involves all components of the joint environment: cartilage, synovium, and subchondral bone. When there is joint injury, such as cranial cruciate ligament (CCL) rupture in dogs or humans, there are abnormal biomechanical stresses placed on the entire joint. Invariably, this leads to loss of the articular cartil...

Costal Versus Articular Chondrocytes in Alginate Three-Dimensional Cultures

Given the difficulties in accessing articular cartilage as a source of chondrocytes to be used in fabricating cartilage constructs, alternative sources are required. The present study examined chondrocytes from costal cartilage for their suitability in cartilage tissue engineering. Chondrocytes isolated from rat knee and rib hyaline cartilage were separately mixed with alginate and placed in a ...

Comparison of Autogenic Costal Cartilage with Chitosan Scaffold in Canine Humeral Defect Healing

Objective- Current trends emphasize the acceleration of fracture healing on the ground that in doing so, the limitation of mobility and complications associated with recovery period are reduced. The present study aims to compare autogenic costal cartilage with Chitosan scaffold in canine humeral defect healing. Design- Experimental study Animal-15 adult male dogs Procedures-...